Age, CDI scores, and years of education were compared between MDD patients and control individuals using two-sample t-tests, whereas gender distributions were compared with Chi-square tests. SPSS 22.0 was used for statistical analyses. Correlations between abnormal ALFF values and specific clinical findings were assessed via Pearson correlation analyses. p < 0.05 were considered significant.
A voxel-by-voxel covariance analysis of individual whole-brain ALFF maps was used to detect differences between the two study cohorts. Analyzed covariates included age, years of education, and framewise displacement. REST was used for the GRF correction of results at p < 0.01 (cluster significance: p < 0.01, voxel significance: p < 0.001).
A voxel-by-voxel covariance analysis of individual whole-brain ALFF maps was used to detect differences between the two study cohorts. Analyzed covariates included age, years of education, and framewise displacement. REST was used for the GRF correction of results at p < 0.01 (cluster significance: p < 0.01, voxel significance: p < 0.001).
Free full text: Click here
