Unilateral Deep Brain Stimulation for Parkinson's Disease

A 68-year-old man who had been diagnosed with PD for 11 years was unilaterally implanted with a Medtronic 3389 electrode in the left GP and a Medtronic Activa PC + S sensing pulse generator (Afshar et al., 2013 (link)). His OFF-meds MDS-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) III motor score (Goetz et al., 2008 (link)) was 50 and freezing of gait questionnaire (Nieuwboer et al., 2009 (link)) score was 13. His levodopa daily equivalent dosage was 1,025 mg (Tomlinson et al., 2010 (link)). He gave informed consent and the protocol was approved by the University of Minnesota Institutional Review Board.

Free full text: Click here

Lu C., Amundsen-Huffmaster S.L., Louie K.H., Petrucci M.N., Palnitkar T., Patriat R., Harel N., Park M.C., Vitek J.L., MacKinnon C.D, & Cooper S.E. (2022). Modulation of Beta Oscillations in the Pallidum During Externally Cued Gait. Frontiers in signal processing, 2, 813509.

Publication 2022

3389 electrode Activa PC + S

Institutional review board Levodopa Parkinson s disease Pulse

Corresponding Organization : University of Minnesota

Top 5 similar protocols

Variable analysis

independent variables

Unilateral implantation of a Medtronic 3389 electrode in the left GP

dependent variables

MDS-UPDRS III motor score
Freezing of gait questionnaire score

control variables

Levodopa daily equivalent dosage

controls

No positive or negative controls were explicitly mentioned.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!