We used the method provided in the pwrEWAS v1.4.0 R/Bioconductor library to perform power analyses across DNAm array platforms (Graw et al., 2019 (link)). Parameters for these analyses included 100 total simulations varying the total samples N from 50 to 850. We targeted 500 DMPs and assessed test group Beta-value differences δ of 0.05, 0.1 and 0.2.
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