The preparation, acquisition, and evaluation of [18F]FDG PET/CT were all performed in accordance with the European Association of Nuclear Medicine (EANM) guidelines [11 (link)].
A 24 h high-fat, low-carbohydrate diet and 6 h fasting time prior to the scan were used in all patients. Additionally, if there were no contra-indications against its use, an intravenous heparin injection of 50 IU/kg was given 15 min prior to the scan to further suppress physiological [18F]FDG uptake. All scans were acquired on the Biograph Vision digital PET/CT system (Siemens Healthineers, Knoxville, TN, USA). Gating was performed using co-registration of an ECG, both for regular gating (single gate) and CardioFreezeTM, and in which the sequences were performed in a single-bed position for 10 min, immediately after the regular non-gated [18F]FDG PET/CT scan had been completed.
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