The QSM reconstruction comprised the total field estimation using an adaptive, quadratic fit of the mGRE phase,48 (link) local field calculation with the projection onto dipole fields (PDF) method,47 (link) and susceptibility estimation using the morphology-enabled dipole inversion with automatic uniform CSF zero-reference algorithm.46 (link),52 (link)-54 (link) In stroke patients, the total field was estimated using a linearfit of the mGRE phase,55 (link) as 3D flow compensation was not available on the clinical scanner. The CBF maps (mL/100 g/min) were generated from the ASL data using FuncTool (GE Healthcare). All images were co-registered and interpolated to the resolution of the QSM maps using the FSL FLIRT algorithm.56 (link),57 (link)
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Multiparametric Quantitative MRI Mapping in Stroke
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Corresponding Organization : Cornell University
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Variable analysis
independent variables
- Adaptive, quadratic fit of the mGRE phase
- Local field calculation with the projection onto dipole fields (PDF) method
- Susceptibility estimation using the morphology-enabled dipole inversion with automatic uniform CSF zero-reference algorithm
- Total field estimation
- Susceptibility maps
- CBF maps (mL/100 g/min)
- Linear fit of the mGRE phase in stroke patients (due to unavailability of 3D flow compensation on the clinical scanner)
- Co-registration and interpolation of images to the resolution of the QSM maps using the FSL FLIRT algorithm
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