Preoperative blood sampling was performed to measure the neutrophil, lymphocyte, and platelet levels for the calculation of the NLR, PLR, and SII indices. NLR and PLR were defined as the total number of neutrophils or platelets divided by the total number of lymphocytes. SII was calculated with the formula SII = (P × N)/L, where P, N, and L refer to peripheral platelet, neutrophil, and lymphocyte counts, respectively.
Prognostic Significance of Inflammatory Indices in CRC
Preoperative blood sampling was performed to measure the neutrophil, lymphocyte, and platelet levels for the calculation of the NLR, PLR, and SII indices. NLR and PLR were defined as the total number of neutrophils or platelets divided by the total number of lymphocytes. SII was calculated with the formula SII = (P × N)/L, where P, N, and L refer to peripheral platelet, neutrophil, and lymphocyte counts, respectively.
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Corresponding Organization :
Other organizations : Sun Yat-sen University, Sun Yat-sen University Cancer Center, The First Affiliated Hospital, Sun Yat-sen University
Protocol cited in 8 other protocols
Variable analysis
- Demographics (age and sex)
- Clinicopathological features (tumor location, tumor size, histological type, and tumor stage)
- Treatment with chemotherapy
- Neutrophil, lymphocyte, and platelet levels
- NLR, PLR, and SII indices
- Cecum carcinoma, ascending colon cancer, and right-half transverse colon were classified as right-sided CRC
- The rest were classified as left-sided CRCs
- The well and moderately differentiated adenocarcinomas were histologically categorized as the well-differentiated type
- The poorly differentiated adenocarcinomas included poorly differentiated adenocarcinoma, mucinous adenocarcinoma, signet ring cell cancer, and undifferentiated cancer
- Tumor staging was performed according to the 7th edition of the Union for International Cancer Control-American Joint Committee on cancer classification for CRC
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