All subjects underwent the same PET scan protocol which included an overnight fast, a dedicated and personalized cooling protocol, and the injection of a fixed activity of approximately 75 MBq 18F-FDG (details can be found in Broeders et al. [14 (link)] and de Ligt et al. [15 (link)]). Imaging was performed using a Gemini™ TF PET/CT system (Philips Healthcare, Eindhoven, The Netherlands). Patients underwent a low-dose non-contrast-enhanced whole-body CT protocol (120 kVp, 30 mAs) for scatter and attenuation correction and anatomical reference imaging.
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