Multimodal Imaging Evaluation of Paranasal Sinus Disorders

CT examinations were carried out using GE Light speed 16-slice and Siemens SOMATOM Definition 40-slice spiral CT scanners. Axial and coronal plain scanning and enhanced axial venous scanning were performed. Scanning parameters: tube current: 300mA; tube voltage: 120kV; matrix: 512x512; layer thickness: 3mm; window width: 250HU; and window level: 50HU. MR examinations were conducted using Siemens 1.5T, GE 3.0T magnetic resonance scanners, and quadrature head coil. Axial and coronal plain scanning, and enhanced axial, coronal and sagittal scanning were performed. Scanning parameters: T1WI: TR=230, TE=2.30; T2WI: TR=2800, TE=82.12; STIR sequences in coronal positions: TR=3200, TE=2.70; matrix: 256x256, layer thickness: 4mm, and interval: 1mm. Contrast-enhanced CT and MR scanning were respectively administered with the contrast agents of non-ionic iodine (ioversol, iohexol, dosage of 1.5ml/kg, flow rate of 3ml/s) and Gd-DTPA (dosage of 0.1mmol/kg, flow rate of 2ml/s) intravenously injected through the cubital vein with high-pressure syringe. The scanning range of CT and MR: the axial scanning was from the upper edge of the frontal sinus to the lower edge of the second cervical vertebra, while the coronal scanning was from the frontal sinus to the posterior edge of the sphenoid sinus, and the sagittal scanning covered the whole nasal cavity and paranasal sinuses.

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Xiang J.Y., Huang X.S., Feng N., Zheng X.Z., Rao Q.P., Xue L.M., Ma L.Y., Chen Y, & Xu J.X. (2023). A diagnostic scoring model of ENKTCL in the nose-Waldeyer’s ring based on logistic regression: Differential diagnosis from DLBCL. Frontiers in Oncology, 13, 1065440.

Publication 2023

Contrast agents Ct scanners Examinations Frontal sinus Gd dtpa Head Iodine Iohexol Ioversol Light Nasal cavity Paranasal sinuses Pressure Second cervical vertebra Sphenoid sinus Syringe Vein

Corresponding Organization : Second Affiliated Hospital of Zhejiang University

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Variable analysis

independent variables

CT scanner type (GE Light speed 16-slice and Siemens SOMATOM Definition 40-slice spiral CT scanners)
MR scanner type (Siemens 1.5T, GE 3.0T magnetic resonance scanners)
Contrast agents (non-ionic iodine, Gd-DTPA)

dependent variables

Axial and coronal plain scanning
Enhanced axial venous scanning (CT)
Axial, coronal and sagittal enhanced scanning (MR)
Scanning parameters (tube current, tube voltage, matrix, layer thickness, window width, window level, TR, TE)

control variables

Scanning range (axial scanning from upper edge of frontal sinus to lower edge of second cervical vertebra, coronal scanning from frontal sinus to posterior edge of sphenoid sinus, sagittal scanning covering the whole nasal cavity and paranasal sinuses)
Contrast agent dosage and flow rate (non-ionic iodine: 1.5ml/kg, 3ml/s; Gd-DTPA: 0.1mmol/kg, 2ml/s)
Intravenous injection through cubital vein using high-pressure syringe

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