We conducted a systematic review of the clinical trial studies focusing on the analysis and comparison of the effectiveness of abiraterone and enzalutamide treatments. The records were found in PubMed, Scopus, and Web of Sciences databases using the following keywords: Enzalutamide, Abiraterone, Prostate Cancer, and randomized controlled trials. Unfortunately, no clinical trial study comparing enzalutamide and abiraterone directly was found. Therefore, the efficacy and survival probability data were extracted from the most recent meta-analysis study that directly focused on the comparison of enzalutamide and Abiraterone. The required efficacy data were progression-free survival and overall survival. In addition, the side effects of taking both drugs were included in the model. Given that the treatment rates were estimated based on annual amplitudes while the study cycles were monthly, all the data were converted to monthly probabilities.
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