In order to determine the sensitivity and reproducibility of the BBB scale14 (link), we compared and correlated the average values of the scores assigned by six independent evaluators to the locomotor capacity functional recovery of 30 male Wistar rats 28 days after laminectomy and induced spinal cord injury (of degree mild, moderate or severe). Images of the movement of each animal were detected simultaneously by three digital cameras and subsequently reviewed by the evaluators, who were blinded to the severity of the injuries.
The experimental model we adopted to induce spinal cord injuries was first developed by MASCIS; our version, standardized for Wistar rats15 , consisted of the following stages:
BBB SCALE
O -No observable movement of the hindlimbs.
The experimental model we adopted to induce spinal cord injuries was first developed by MASCIS; our version, standardized for Wistar rats15 , consisted of the following stages:
BBB SCALE
O -No observable movement of the hindlimbs.
