DXA scans were performed on the whole body to assess total body with head BMD (TB-BMD) and bone mineral content (TB-BMC) and on the lumbar spine to assess spinal BMD (SP-BMD) of L1-L4, using Hologic QDR 4500, Delphi or Discovery (Hologic, Waltham, MA) or Lunar DPX, DPXL or Prodigy (GE Medical Systems, Madison, WI) machines. Fat and lean mass (body composition) measures included total body fat mass (TBF), trunk fat (TrF), extremity (arms and legs) fat (ExF) and extremity lean mass (ExL). The Body Composition Analysis Center at Tufts University School of Medicine analyzed all scans to standardize across machines and clinical sites. [5 (link), 16 (link)] Results were available on 379 of 386 enrollees (four were not ambulatory, two were too heavy for the machine and one had no results).
Protocol detail
Body Composition Assessment via DXA Scans
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Corresponding Organization : Cancer Research And Biostatistics
Other organizations : Children's Hospital of Los Angeles, San Francisco General Hospital, University of California, San Francisco
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Variable analysis
independent variables
- None explicitly mentioned
- Total body bone mineral density (TB-BMD)
- Total body bone mineral content (TB-BMC)
- Spinal bone mineral density (SP-BMD) of L1-L4
- Total body fat mass (TBF)
- Trunk fat (TrF)
- Extremity (arms and legs) fat (ExF)
- Extremity lean mass (ExL)
- The Body Composition Analysis Center at Tufts University School of Medicine analyzed all scans to standardize across machines and clinical sites
- Positive controls: None mentioned
- Negative controls: None mentioned
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