NMR spectra
were obtained on Bruker AV-400
and AV-600 MHz spectrometers. The 1H NMR chemical shifts
were measured relative to CDCl3 or DMSO-d6 as the internal reference (CDCl3: δ
= 7.26 ppm; DMSO-d6: δ = 2.50 ppm).
The 13C NMR chemical shifts were given using CDCl3 as the internal standard (CDCl3: δ = 77.16 ppm;
DMSO-d6: δ = 39.52 ppm). Melting
points were determined with XRC-1 and uncorrected. High-resolution
mass spectra (HRMS) were obtained with a Waters-Q-TOF-Premier (ESI).
Unless otherwise noted, all reagents were obtained from commercial
suppliers and used without further purification. Thiophene 1,1-dioxide
derivatives were prepared according to the literature procedures.15 (link) Arylboronic acids were purchased from Energy
Chemical. DCE, DMF, and DMSO were dried by refluxing over CaH2. Toluene and 1,4-dioxane were dried by refluxing over Na
and freshly distilled prior to use.
were obtained on Bruker AV-400
and AV-600 MHz spectrometers. The 1H NMR chemical shifts
were measured relative to CDCl3 or DMSO-d6 as the internal reference (CDCl3: δ
= 7.26 ppm; DMSO-d6: δ = 2.50 ppm).
The 13C NMR chemical shifts were given using CDCl3 as the internal standard (CDCl3: δ = 77.16 ppm;
DMSO-d6: δ = 39.52 ppm). Melting
points were determined with XRC-1 and uncorrected. High-resolution
mass spectra (HRMS) were obtained with a Waters-Q-TOF-Premier (ESI).
Unless otherwise noted, all reagents were obtained from commercial
suppliers and used without further purification. Thiophene 1,1-dioxide
derivatives were prepared according to the literature procedures.15 (link) Arylboronic acids were purchased from Energy
Chemical. DCE, DMF, and DMSO were dried by refluxing over CaH2. Toluene and 1,4-dioxane were dried by refluxing over Na
and freshly distilled prior to use.
