Protocol detail

Murine Model of Malignant Pleural Disease

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Ekeke C.N., Russell K.L., Murthy P., Guo Z.S., Soloff A.C., Weber D., Pan W., Lotze M.T, & Dhupar R. (2020). Intrapleural interleukin-2–expressing oncolytic virotherapy enhances acute antitumor effects and T-cell receptor diversity in malignant pleural disease. The Journal of thoracic and cardiovascular surgery, 163(4), e313-e328.

Publication 2020

anti–PD-1 antibody (clone RMP1–14;

After treatment Anti antibody Cell Clone Delivery Inoculation Isoflurane Light Luciferase Luciferin Mice Oxygen Parenteral Peritoneal Phosphate Saline Spleen Tissue Tumor Tumor burden Tumor inoculation Viruses

Corresponding Organization : VA Pittsburgh Healthcare System

Other organizations : HudsonAlpha Institute for Biotechnology, iRepertoire (United States), UPMC Hillman Cancer Center

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