To calculate the sample size for the cortical bone thickness analysis, the estimated cortical bone thickness from a previous relevant study that investigated the tibia and fibula was utilised [41 (link)]. Using the one-way analysis of variance, a 2-sided type I error of 0.05, 90% power, a minimum sample of 18 per area was required (nQuery Advisor® Version 6.01; Statistical Solutions Ltd., Saugus, MA, USA). More samples were analysed to spare the number of specimens in case dropout during the study. The total number of investigated specimens in this study was 24.
Cortical Bone Thickness Analysis of the Tibia and Fibula
To calculate the sample size for the cortical bone thickness analysis, the estimated cortical bone thickness from a previous relevant study that investigated the tibia and fibula was utilised [41 (link)]. Using the one-way analysis of variance, a 2-sided type I error of 0.05, 90% power, a minimum sample of 18 per area was required (nQuery Advisor® Version 6.01; Statistical Solutions Ltd., Saugus, MA, USA). More samples were analysed to spare the number of specimens in case dropout during the study. The total number of investigated specimens in this study was 24.
Corresponding Organization : Tokyo Medical and Dental University
Variable analysis
- Cortical bone thickness measured at different locations in the axial slices at the adductor tubercle and MEC levels
- Cortical bone thickness
- Measurement approach (single observer randomly measured the specimens twice on different days in the same approach)
- Statistical significance level (p < 0.05)
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