This study aims to show feasibility of C-Tr-RPD. The main study endpoint was therefore a composite index made by conversion to open surgery due to inability to complete triangle dissection or need to use energy devices to do so (i.e., harmonic shears and/or radiofrequency or microwave-powered devices).
Secondary study endpoints were incidence and severity of postoperative complications [18 (link)], post-pancreatectomy hemorrhage (PPH) [19 (link)], delayed gastric emptying (DGE) [20 (link)], and chyle leak [21 (link)]. Postoperative complications ≥ grade III, according to Clavien–Dindo [18 (link)], were considered severe complications. The cumulative burden of postoperative complications was estimated using the comprehensive complication index (CCI) [22 (link)].
The following parameters were also recorded: operative time, pylorus preservation, need and type of vascular resection [23 (link)], length of hospital stay, 90-day hospital readmission, 90-day mortality, 90-day mortality following completion of the learning curve [24 (link)], reoperation, and interventional procedures.
All specimens were analyzed according to the LEEPP protocol [25 (link)], as previously reported in detail [26 (link)]. Seven margins were assessed: anterior surface, posterior surface, vein bed, SMA groove, pancreatic neck, proximal duodenum/stomach, and common bile duct. Margins were defined positive (R1) if tumor cells were detected ≤ 1 mm of any margin.
Additional pathology data included tumor type (i.e., PDAC or malignant IPMN), tumor size, T status, N status, presence of perineural infiltration, number of examined lymph nodes, and number of metastatic lymph nodes.
Secondary study endpoints were incidence and severity of postoperative complications [18 (link)], post-pancreatectomy hemorrhage (PPH) [19 (link)], delayed gastric emptying (DGE) [20 (link)], and chyle leak [21 (link)]. Postoperative complications ≥ grade III, according to Clavien–Dindo [18 (link)], were considered severe complications. The cumulative burden of postoperative complications was estimated using the comprehensive complication index (CCI) [22 (link)].
The following parameters were also recorded: operative time, pylorus preservation, need and type of vascular resection [23 (link)], length of hospital stay, 90-day hospital readmission, 90-day mortality, 90-day mortality following completion of the learning curve [24 (link)], reoperation, and interventional procedures.
All specimens were analyzed according to the LEEPP protocol [25 (link)], as previously reported in detail [26 (link)]. Seven margins were assessed: anterior surface, posterior surface, vein bed, SMA groove, pancreatic neck, proximal duodenum/stomach, and common bile duct. Margins were defined positive (R1) if tumor cells were detected ≤ 1 mm of any margin.
Additional pathology data included tumor type (i.e., PDAC or malignant IPMN), tumor size, T status, N status, presence of perineural infiltration, number of examined lymph nodes, and number of metastatic lymph nodes.
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