We extracted 10,433 experimentally validated MHC class II binders or T-helper epitopes from Immune Epitope Database (IEDB) [53 (link)]. Out of these 10,433 MHC class II binders, 3705 induced IFN-γ, whereas remaining 6728 unique peptides have not induced IFN-γ. Thus, our dataset contains 3705 positive examples or IFN-γ inducing peptides and 6728 negative examples or IFN-γ non-inducing peptides.
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