The LMRGs were obtained from the Molecular Signature Database (MsigDB, v7.5.1, https://www.gsea-msigdb.org/) (22 (link)), including the following pathways: glycerophospholipid metabolism, adipocytokine signing pathway, PPAR signaling pathway, glycerolipid metabolism, regulation of lipolysis in adipocytes, fatty acid metabolism, arachidonic acid metabolism, sphingolipid metabolism, cholesterol metabolism, fatty acid degradation, ether lipid metabolism, steroid hormone biosynthesis, fatty acid elongation, fat digestion and absorption, biosynthesis of unsaturated fatty acids, steroid biosynthesis, linoleic acid metabolism, alpha-linolenic acid metabolism, primary bile acid biosynthesis (Table S1). The LMRGs were further filtered by intersecting with DEGs between glioma and brain tissue samples in the TCGA dataset.
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