Transdermal Delivery of Anti-Inflammatory Agents

The FA was received as a gift sample from NZ Fulvic Ltd., New Zealand. TQ, DPPH, and Rhodamine B were purchased from Sigma-Aldrich (Darmstadt, Germany). Transcutol P, Capryol 90, Labrasol, Plurol, Polyethylene glycol, Tween 20, Tween 80, and PEG 200 were obtained from Gattefosse Pvt. Ltd., Mumbai, India as gift samples. TNF-α and IL-6 ELISA Kits were purchased from Krishgen Biosystem (Mumbai, India). Imiquimod (IMQ) 5% cream (Glenmark Pharmaceuticals Ltd. Imiquad^®, (Delhi, India) was purchased from a local pharmacy. Castor oil, Kalonji oil, lavender oil, sunflower oil, and olive oil were procured from local market, and Carbopol-971 was purchased from GLR Innovations India Pvt. Ltd. (New Delhi, India). All other chemicals and solvents used were of analytical grade.

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Khan R., Mirza M.A., Aqil M., Alex T.S., Raj N., Manzoor N., Naseef P.P., Saheer Kuruniyan M, & Iqbal Z. (2023). In Vitro and In Vivo Investigation of a Dual-Targeted Nanoemulsion Gel for the Amelioration of Psoriasis. Gels, 9(2), 112.

Publication 2023

DPPH Rhodamine B

Capryol 90 Carbopol Castor oil Elisa Imiquimod Innovations Kalonji Labrasol Lavender oil Olive oil Pharmaceuticals Polyethylene glycol Rhodamine b Solvents Sunflower oil Tnf α Transcutol p Tween 20 Tween 80

Corresponding Organization : Jamia Hamdard

Other organizations : Jamia Millia Islamia, Moulana Hospital, King Khalid University

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Variable analysis

independent variables

Fulvic acid (FA) from NZ Fulvic Ltd., New Zealand
Transcutol P, Capryol 90, Labrasol, Plurol, Polyethylene glycol, Tween 20, Tween 80, and PEG 200 from Gattefosse Pvt. Ltd., Mumbai, India
Castor oil, Kalonji oil, lavender oil, sunflower oil, and olive oil from local market
Carbopol-971 from GLR Innovations India Pvt. Ltd. (New Delhi, India)
Imiquimod (IMQ) 5% cream (Glenmark Pharmaceuticals Ltd. Imiquad®, (Delhi, India)

dependent variables

TNF-α and IL-6 levels (measured using ELISA kits purchased from Krishgen Biosystem, Mumbai, India)

control variables

TQ, DPPH, and Rhodamine B (purchased from Sigma-Aldrich, Darmstadt, Germany)
All other chemicals and solvents used were of analytical grade

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