89Zr was produced through the 89Y(p,n)89Zr reaction on an EBCO TR19/9 variable-beam energy cyclotron (Ebco Industries Inc., British Columbia, Canada) at Memorial Sloan Kettering Cancer Center. The crude product was purified in accordance with previously reported methods to yield 89Zr with a specific activity of 5.3−13.4 mCi/µg.36 (link) Dose measurements were made using a Capintec CRC-15R Dose Calibrator (Capintec, Ramsey, NJ).
Protocol detail
Zirconium-89 Production and Purification
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Cancer
Cyclotron
Ebco
Corresponding Organization :
Other organizations : Icahn School of Medicine at Mount Sinai, City University of New York, Hunter College, The Graduate Center, CUNY, Academic Medical Center, Cornell University
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Variable analysis
independent variables
- Beam energy of the EBCO TR19/9 variable-beam energy cyclotron
- Specific activity of the produced ^{89}Zr
- Bombardment target material (^{89}Y)
- Purification method
- Dose measurement equipment (Capintec CRC-15R Dose Calibrator)
- Positive control: Not mentioned
- Negative control: Not mentioned
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