Evaluating Disease Resistance in Commercial Pigs

All tests have been performed on commercial pigs from high health farms with donation of swine genetic materials as part of the Consortium. For each trial one company was requested to provide 200 pigs at weaning from PRRSV negative (PRRSV-), Mycoplasma hyopneumoniae-, and swine influenza virus- farms, and if possible from porcine circovirus type 2 (PCV2) free farms. Pigs could be from vaccinated sows since maternal antibody prevents them from becoming infected with PCV2. The source populations were crossbred commercial pigs (Genus/PIC USA; Newsham Choice Genetics; Fast Genetics; Genetiporc, Inc.; Genesus Genetics) with complete parentage and pedigree records. Since SNP chips are used for genotyping there was a decreased need for extensive family structure. There was no preselection of sires for disease traits. Pigs (~200/trial) were transported to the biosecure Kansas State University (KSU) testing facility at weaning. All pig experiments were initiated after approval by KSU IACUC and IBC institutional committees. After arrival pigs were treated with broad spectrum antibiotics for 1 week, to prevent expression of other organisms.

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Lunney J.K., Steibel J.P., Reecy J.M., Fritz E., Rothschild M.F., Kerrigan M., Trible B, & Rowland R.R. (2011). Probing genetic control of swine responses to PRRSV infection: current progress of the PRRS host genetics consortium. BMC Proceedings, 5(Suppl 4), S30.

Publication 2011

Antibiotics Antibody Chips Family structure Genetic materials Iacuc Maternal Mycoplasma hyopneumoniae Pigs Populations Porcine circovirus Prrsv Swine influenza virus

Corresponding Organization :

Other organizations : Agricultural Research Service, Michigan State University, Iowa State University, Kansas State University

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Protocol cited in 7 other protocols

Variable analysis

independent variables

Source populations of crossbred commercial pigs (Genus/PIC USA; Newsham Choice Genetics; Fast Genetics; Genetiporc, Inc.; Genesus Genetics)

dependent variables

Disease traits

control variables

Pigs from PRRSV negative (PRRSV-), Mycoplasma hyopneumoniae-, and swine influenza virus- farms, and if possible from porcine circovirus type 2 (PCV2) free farms
Pigs from vaccinated sows (since maternal antibody prevents them from becoming infected with PCV2)
No preselection of sires for disease traits
Broad spectrum antibiotics for 1 week after arrival to prevent expression of other organisms

positive controls

None specified

negative controls

None specified

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