Blood was collected in 10 mL Vacuette serum clot-activator tubes (Greiner Bio-one, product number 455092) before 12 AM. Blood was allowed to clot for 30 min at room temperature and serum was stored in aliquots at −80°C in the Auria Biobank (Turku, Finland) within 2 hours of sampling. Frozen samples were shipped on dry ice to Basel, Switzerland, where sNfL concentrations were measured by a single molecule array assay (Simoa Technology).14 15 (link)
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Blood Sampling and sNfL Analysis
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Corresponding Organization : Turku PET Centre
Other organizations : Åbo Akademi University, University of Turku, Turku University Hospital, University of Basel, University Hospital of Basel
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Variable analysis
independent variables
- Not explicitly mentioned
- Soluble neurofilament light (sNfL) concentrations
- Blood collected in 10 mL Vacuette serum clot-activator tubes (Greiner Bio-one, product number 455092)
- Blood allowed to clot for 30 min at room temperature
- Serum stored in aliquots at −80°C in the Auria Biobank (Turku, Finland) within 2 hours of sampling
- Frozen samples shipped on dry ice to Basel, Switzerland
- No positive or negative controls were explicitly mentioned in the provided information.
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