The experimental groups were divided into 5 groups and 10 rats in each group. The characteristics of the groups are as follows: Group 1: Control Group, Group 2: has cecal ligation and perforation (CLP), Group 3: has 50 mg/kg of silymarin and CLP (SM50+CLP), Group 4: has 100 mg/kg of silymarin and CLP (SM100+CLP) and Group 5: has 200 mg/kg of silymarin and CLP (SM200+CLP).
Protocol detail
Silymarin's Effects on Sepsis-Induced Injury
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Other organizations : Atatürk University
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Variable analysis
independent variables
- Silymarin dose (50 mg/kg, 100 mg/kg, 200 mg/kg)
- Outcome(s) of cecal ligation and perforation (CLP)
- Number of rats per group (10)
- Presence or absence of cecal ligation and perforation (CLP)
- Positive control: Group 2 (CLP)
- Negative control: Group 1 (Control Group)
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