Serum Biomarkers Monitoring in Hypercholesterolemia

Several other serum parameters were measured using Roche Cobas 8000 analyzer system to monitor the effect of diet-induced hypercholesterolemia as well as Stellaria media treatment on liver and kidney functions. Total protein, albumin, and creatinine concentrations as well as alkaline phosphatase (ALP) enzyme activities were analyzed by colorimetric assays from Roche (Mannheim, Germany). Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) enzyme activities and carbamide levels were measured with Roche UV assays (Mannheim, Germany), as described earlier [14 (link)].

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Demján V., Kiss T., Siska A., Szabó M.R., Sárközy M., Földesi I., Csupor D, & Csont T. (2020). Effect of Stellaria media Tea on Lipid Profile in Rats. Evidence-based Complementary and Alternative Medicine : eCAM, 2020, 5109328.

Publication 2020

Cobas 8000 analyzer system

Alanine aminotransferase Albumin Alkaline phosphatase Aspartate aminotransferase Assays Carbamide Colorimetric Creatinine Diet Enzyme activities Hypercholesterolemia Kidney Liver Protein Serum Stellaria media

Corresponding Organization : University of Szeged

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Variable analysis

independent variables

Diet-induced hypercholesterolemia
Stellaria media treatment

dependent variables

Total protein concentration
Albumin concentration
Creatinine concentration
Alkaline phosphatase (ALP) enzyme activity
Alanine aminotransferase (ALT) enzyme activity
Aspartate aminotransferase (AST) enzyme activity
Carbamide levels

control variables

Control variables not explicitly mentioned.

controls

No positive or negative controls were specified by the authors.

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