We expected landscapes of two closely related species to be more correlated than the landscapes of two distantly related species. Thus, the correlation between any two landscapes of diversity and divergence is expected to depend on distances between them in the phylogenetic tree. We decided to plot our correlations against distance (in generations) between the most common recent ancestor (MRCA) of each landscape. In comparing two landscapes of diversity, this amounts to the total distance between the two tips in the species tree. For instance, the phylogenetic distance between diversity in humans and diversity in bonobos is the sum of the lengths of the human, pan and bonobo branches in the species tree (
Comparative Genomic Landscapes Analysis
We expected landscapes of two closely related species to be more correlated than the landscapes of two distantly related species. Thus, the correlation between any two landscapes of diversity and divergence is expected to depend on distances between them in the phylogenetic tree. We decided to plot our correlations against distance (in generations) between the most common recent ancestor (MRCA) of each landscape. In comparing two landscapes of diversity, this amounts to the total distance between the two tips in the species tree. For instance, the phylogenetic distance between diversity in humans and diversity in bonobos is the sum of the lengths of the human, pan and bonobo branches in the species tree (
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Corresponding Organization : University of Oregon
Variable analysis
- Phylogenetic distance between the most common recent ancestor (MRCA) of each landscape
- Spearman correlation between the landscapes of diversity and divergence across windows within a chromosome
- Chromosome 12 (one of the smallest chromosomes in the great apes, with no major inversions, and good variation in exon density and recombination rate)
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