Cytological Examination of Canine Bile

Bile samples collected from control dogs underwent cytological examination by an American College of Veterinary Pathology certified study investigator (D.S.). Each cytological specimen was prepared at the time of bile collection by smearing a drop of bile onto each of 2 individual glass microscope slides. Slides were air-dried, fixed, and stained with hematoxylin and eosin. Samples of gallbladder mucus from dogs with mucocele formation were not examined cytologically.

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Gookin J.L., Hartley A.N., Aicher K.M., Mathews K.G., Cullen R., Cullen J.M., Callahan B.J., Stowe D.M., Seiler G.S., Jacob M.E., Arnold J.W., Azcarate-Peril M.A, & Stauffer S.H. (2023). Gallbladder microbiota in healthy dogs and dogs with mucocele formation. PLOS ONE, 18(2), e0281432.

Publication 2023

Bile Dogs Eosin Gallbladder Microscope Mucocele Mucus

Corresponding Organization : University of North Carolina at Chapel Hill

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Cytological examination of bile samples

control variables

Bile samples collected from control dogs
Cytological specimens prepared by smearing a drop of bile onto glass microscope slides
Slides were air-dried, fixed, and stained with hematoxylin and eosin

controls

Samples of gallbladder mucus from dogs with mucocele formation were not examined cytologically (negative control)

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