Exposure to gabapentinoids and outcomes (clinical efficacy, adverse effects) were recorded for all those patients who continued the treatment till 8-weeks of the study. Clinical efficacy was defined as a change in mean pain score from baseline to a clinically meaningful reduction of ≥30% or ≥50%.16 (link) Data was converted to electronic files using the Microsoft Excel Software and Excel files were imported to Statistical Package for Social Sciences (SPSS) version 22 for analysis. The quantitative variables like age, dosage of drugs, time to onset of pain relief and difference in pain scores were presented with Mean and Standard Deviations (SD). The qualitative variables such as ethnicity, gender and adverse effects were reported in frequency and percentage. For making comparison of pain scores, time to relief in pain between groups i.e. pregabalin and gabapentin, we used two independent samples Student ‘t’ test. Statistical significance was set at p-value less than 0.05.
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