To ascertain the pH responsiveness of the quince/mucin-co-poly (methacrylate) hydrogel, swelling of the hydrogel discs was investigated in an acidic buffer with a pH of 1.2, and a phosphate buffer with a pH of 6.8 or 7.4 at 37 °C. Pre-weighed discs were immersed in the buffer solution, and, after pre-determined time intervals (1, 2, 3, 4, 6, 8, 10, 12, 14, 16, 18, 20, 24, 28, 32 and 36 h), the discs were removed, allowed to drop off excessive immersion medium from their surface, and reweighed. The swelling capacity g/g was calculated using the following equation:
where Wt denotes the weight of the disc after time t, and Wo represents the initial weight of the dried disc.
where Wt denotes the weight of the disc after time t, and Wo represents the initial weight of the dried disc.
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