Sour Cherry Chewing Gum Preparation

Chewing gum preparation: Sour cherry chewing gum and placebo chewing gum were produced in the Department of Pharmaceutical Technology, which is licensed to produce chewing gum containing sour cherry extract. The sour cherry gum used in this investigation was prepared in the same way as described in our previous studies, Homoki et al. [25 (link)] and Skopko et al. [27 (link)]. Based on our earlier work, the main ingredients of the chewing gum were Geminis T BHA gum (Cafosa) base, xylitol, citric acid, glycerol, saccharine (Sigma), peppermint volatile oil, and sour cherry extract [27 (link)]. The flavoring ingredients (saccharine, citric acid, and glycerol) were dissolved in purified water. In the case of the sour cherry gum, 0.1 g of the anthocyanin-containing sour cherry extract was also added to this mixture. The emulsifying of the water phase was made into the melted gum stock at 60 °C, and then the peppermint oil was mixed in at 40 °C. The gum material was blocked out into 2.5 g pelleted tablets. Finally, after controlling the room temperature for 12 h, the pellets were placed into paper boxes and stored at 8–15 °C [25 (link),27 (link)].