The primary end point was intracranial progression-free survival (iPFS) with secondary end points of extracranial progression-free survival (ePFS) and overall survival (OS). Objective intracranial response rate was defined as the proportion of patients who achieved CR or PR. Clinical benefit rate was the proportion of patients with stable disease for ≥6 months or achieved CR or PR among all evaluable patients. Patients who had stable disease for ≥6 months were considered unevaluable for that measure.
Protocol detail
Intracranial Progression-Free Survival
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Disease 6
Patients
Corresponding Organization :
Other organizations : Memorial Sloan Kettering Cancer Center
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Variable analysis
independent variables
- Not explicitly mentioned
- Intracranial progression-free survival (iPFS)
- Extracranial progression-free survival (ePFS)
- Overall survival (OS)
- Objective intracranial response rate (proportion of patients who achieved CR or PR)
- Clinical benefit rate (proportion of patients with stable disease for ≥6 months or achieved CR or PR among all evaluable patients)
- Not explicitly mentioned
- No positive or negative controls were explicitly mentioned in the provided information.
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