We performed descriptive statistics based on demographic variables to obtain absolute and relative variations. We also constructed measurements for disease occurrence, including in-hospital mortality (%), incidence, and countrywide mortality rates. For the burden of disease analysis, the “lillies” package of the R was used to estimate YLL for patients with a given condition (20 (link)), the calculation methodology was based on the number of cases in a population with the diagnosis of a specific disease or condition, using the age of diagnosis of the disease for the cases studied, the Ecuadorian population, and the annual projection for each year based on the life expectancy of the population studied for Ecuador (21 (link)).
The analysis of the data was performed using the SPSS statistics software for Mac (IBM Corp. 2014, version 24.0. Armonk, NY, USA) and R version 3.6.2. Figures and graphs were performed in Prism 8 GraphPad Software version 8.2.0 (2365 Northside Dr. Suite San Diego, CA 92108). The basic cartography maps were generated using QGIS Development Team 180 2.8 (Creative Commons Attribution-ShareAlike 3.0 license CC BY-SA).
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