An area under the receiver operating characteristic (AUROC) test was used to assess the internal and external validity and the chunk- and branch-level accuracy. First, we tested the performance of the algorithm in a set of independent stroke patients with ICAS. The structural dissimilarities in the cerebral arterial configuration between the healthy standard controls and those with stroke with ICAS were expected to indicate the clinical relevance of this algorithm in subjects with pathological conditions.
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