Both T2w and T1w MRI images were acquired on a 3-Tesla MRI scanner (3T Ingenia, Philips Healthcare, Amsterdam, the Netherlands) under an IRB-approved protocol. Six lung cancer patients were scanned in a body mold with both arms up for all MR acquisitions in the coronal direction. In brief, high-resolution (HR: 2x2x2 mm3) T2w RC-4DMRI was acquired using a pulse sequence of a single-shot, turbo spin-echo with echo/repetition time 80/5000-7000 ms and flip angle 90°, together with SENSE (2.0) and partial Fourier (0.7) for acceleration. An MR navigator box was placed at the right diaphragm dome to serve as an internal respiratory surrogate to trigger a prospective RC-4DMRI acquisition. Three respiratory bins were utilized with a narrow acquisition amplitude level (window) and the scanning time was about 5 minutes. More T2w RC-4DMRI acquisition details were described before8 (link).
T1w 3D cine images in BH (HR: 2x2x2 mm3) and FB (LR: 5x5x5 mm3, 2Hz) were acquired using multi-shot, fast turbo field echo with echo/repetition time 1.9/4.2 ms and flip angle 15°, together with SENSE (4 for HR and 6 for LR) and partial Fourier (0.8) approximation. A BH scan took 20 s and the FB scan lasted 40 s at a 2Hz frame rate. The field of view was set the same for T1w and T2w scans, covering the full lungs and liver. More details of BH and FB 3D cine MR acquisition can be found elsewhere17 (link).
T1w 3D cine images in BH (HR: 2x2x2 mm3) and FB (LR: 5x5x5 mm3, 2Hz) were acquired using multi-shot, fast turbo field echo with echo/repetition time 1.9/4.2 ms and flip angle 15°, together with SENSE (4 for HR and 6 for LR) and partial Fourier (0.8) approximation. A BH scan took 20 s and the FB scan lasted 40 s at a 2Hz frame rate. The field of view was set the same for T1w and T2w scans, covering the full lungs and liver. More details of BH and FB 3D cine MR acquisition can be found elsewhere17 (link).
