Cerebral Cortex Blood Flow in Mice

The cerebral cortex blood flow of mice was measured as previously reported by Tian H. et al. [9 (link)]. Briefly, blood flow in the cerebral cortex of mice (BALB/c, 6-week-old, either sex) was monitored after scalp avulsion by laser-speckle imaging system (RFLSI Pro, RWD Life Science, Shenzhen, China) under an anesthesia respirator (R540IP, RWD Life Science). The real-time blood flow was monitored before and after tail vein injection of mucetin and stejnulxin.

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Long C., Liu M., Tian H., Li Y., Wu F., Mwangi J., Lu Q., Mohamed Abd El-Aziz T., Lai R, & Shen C. (2020). Potential Role of Platelet-Activating C-Type Lectin-Like Proteins in Viper Envenomation Induced Thrombotic Microangiopathy Symptom. Toxins, 12(12), 749.

Publication 2020

RFLSI Pro R540IP

Anesthesia Avulsion Blood flow Cerebral blood flow Cortex Mice Respirator Scalp Tail Vein

Corresponding Organization : St. Michael's Hospital

Other organizations : University of Chinese Academy of Sciences, University of Science and Technology of China, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Minia University, The University of Texas Health Science Center at San Antonio

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Variable analysis

independent variables

Mucetin
Stejnulxin

dependent variables

Cerebral cortex blood flow

control variables

Mouse strain (BALB/c)
Mouse age (6-week-old)
Mouse sex (either sex)
Anesthesia respirator (R540IP, RWD Life Science)

controls

Positive control: Tail vein injection of mucetin
Negative control: Tail vein injection of stejnulxin

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