Integrative Multi-omics Analysis of Esophageal Cancer

All data were obtained from ArrayExpress, unless stated otherwise. Human tissue RNA-seq data were obtained from: OCCAMS consortium (European Genome-Phenome Archive, EGAD00001007496). Human tissue ATAC-seq data were obtained from: E-MTAB-5169 (Britton et al., 2017 (link)), E-MTAB-6751 (Rogerson et al., 2019 (link)), and E-MTAB-8447 (Rogerson et al., 2020 (link)). The Cancer Genome Atlas OAC ATAC-seq data were obtained from the GDC data portal (https://portal.gdc.cancer.gov/; Corces et al., 2018 (link)). OE19 H3K27ac ChIP-seq was obtained from: E-MTAB-10319 (Ogden et al., 2022 (link)). GAC H3K4me1 and H3K4me3 ChIP-seq were obtained from: Gene Expression Omnibus, GSE75898 (Ooi et al., 2016 (link)). OE19 siKLF5 RNA-seq and KLF5 ChIP-seq were obtained from: E-MTAB-8446 and E-MTAB-8568, respectively (Rogerson et al., 2020 (link)). OE19 dnFOS RNA-seq was obtained from E-MTAB-10334 (Ogden et al., 2023 (link)).