Dynamic Liver MRI with Gadoxetate-Disodium

All patients underwent MRI exam via 3.0-T Magnetom Trio Tim (Siemens Medical Solutions, Erlangen, Germany), Intera Achieva or Ingenia (Philips Medical Systems, Best, the Netherlands), or Discovery MR750w MRI unit (GE Medical Systems, Waukesha, Wis). Dynamic liver MRI was performed using 10mL of gadoxetate-disodium (Primovist; Bayer AG, Berlin, Germany) at an injection rate of 1mL/sec, followed by 20mL of 0.9% saline chaser at the same flow rate (Spectris Solaris MR Injection System; Medrad, Warrendale, PA) [20 (link)]. T1 weighted 3D gradient-echo hepatobiliary phase (HBP) was obtained 20 minutes after contrast agent injection. Other MRI sequences included in routine dynamic liver MRI are written in the S1 Text.

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Park J.H., Chung Y.E., Seo N., Choi J.Y., Park M.S, & Kim M.J. (2021). Hepatobiliary phase signal intensity: A potential method of diagnosing HCC with atypical imaging features among LR-M observations. PLoS ONE, 16(9), e0257308.

Publication 2021

Magnetom Trio Tim Intera Achieva Ingenia Primovist Spectris Solaris MR Injection System

0 9 saline Contrast agent Echo Gadoxetate disodium Liver Patients Primovist Tim 3 Trio

Corresponding Organization : Yonsei University

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Variable analysis

independent variables

MRI exam via 3.0-T Magnetom Trio Tim (Siemens Medical Solutions, Erlangen, Germany), Intera Achieva or Ingenia (Philips Medical Systems, Best, the Netherlands), or Discovery MR750w MRI unit (GE Medical Systems, Waukesha, Wis)
Gadoxetate-disodium (Primovist; Bayer AG, Berlin, Germany) injection (10mL) at an injection rate of 1mL/sec, followed by 20mL of 0.9% saline chaser at the same flow rate

dependent variables

T1 weighted 3D gradient-echo hepatobiliary phase (HBP) obtained 20 minutes after contrast agent injection

control variables

Spectris Solaris MR Injection System (Medrad, Warrendale, PA) used for contrast agent and saline injection

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