PET images were acquired using a Biograph mCT PET/CT scanner (Siemens Medical Solutions) in Seoul [11 (link)]; Discovery and Discovery MI PET scanners (GE medical systems) in BioFINDER 1 and 2, respectively [5 (link), 6 (link)]; a Biograph 6 Truepoint PET/CT scanner (Siemens Medical Solutions) for UCSF patients [18 (link)], a Siemens High-Resolution Research Tomograph (HRRT) scanner in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts. All PET data were locally reconstructed into 4 × 5-min frames for the 80–100-min ([18F]flortaucipir) and 70–90-min ([18F]RO948) intervals post-injection. MR images were acquired on a 3.0T Discovery MR750 scanner (GE medical systems) in Seoul [11 (link)], 3.0T Tim Trio or Skyra scanner (Siemens Medical Solutions) in BioFINDER [5 (link), 6 (link)], a 3.0T Tim Trio or Prisma scanner (Siemens Medical Solutions) at UCSF [18 (link)], a 3.0 Tim Trio scanner (Siemens Medical Solutions) in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts.