Measuring Body Composition with DEXA and BIA

Total body fat mass and total bone-free lean mass (kg) were acquired from total body scans using fan-beamed dual-energy x-ray absorptiometry (Hologic, Waltham, MA or Lunar, Madison, WI) using standardized protocols (35 (link),36 (link)). Appendicular lean mass (ALM) was the sum of lean mass from both arms and legs. Participants missing lean mass measurements for an arm or leg were excluded. The validity and reproducibility of dual-energy x-ray absorptiometry have been reported previously. In Invecchiare in Chianti, body composition was measured using peripheral quantitative computed tomography of the calf. For Invecchiare in Chianti, estimated ALM was available only in men and was derived from equations from Osteoporotic Fractures in Men Study that included height, weight, waist circumference, fat area, muscle area, and muscle density. In Age, Gene/Environment Susceptibility-Reykjavik Study, body composition was measured with bioelectrical impedance (Xitron Hydra ECF/ICF Bio-Impedance Spectrum Analyzer).

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Studenski S.A., Peters K.W., Alley D.E., Cawthon P.M., McLean R.R., Harris T.B., Ferrucci L., Guralnik J.M., Fragala M.S., Kenny A.M., Kiel D.P., Kritchevsky S.B., Shardell M.D., Dam T.T, & Vassileva M.T. (2014). The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 69(5), 547-558.

Publication 2014

Bioelectrical impedance Body composition Body fat Bone mass Computed tomography Dual energy x ray absorptiometry Fractures Gene susceptibility Hydra Lunar Muscle Total body scans Waist circumference

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Other organizations : University of Pittsburgh, California Pacific Medical Center, University of Maryland, Baltimore, Beth Israel Deaconess Medical Center, Harvard University, Hebrew SeniorLife, National Institutes of Health, University of Central Florida, UConn Health, Wake Forest University, Columbia University, Foundation for the National Institutes of Health

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