Comprehensive Neurocognitive Assessment Protocol

SNSB includes Korean version of the mini-mental state examination (K-MMSE),^{[6 (link)]} CDR, Korean version of activities of daily living,^{[7 ]} attention (digit span test), language (Boston naming test, tests for comprehension/repetition/fluency), visuospatial function (Rey Complex Figure Test), verbal and visual memory function (Seoul Verbal Learning Test and Rey complex figure test recall test), and frontal executive function (contrasting program, go-no-go, Controlled Oral Word Association Test, and Stroop test).^{[4 ]} Age, sex, and education-specific norms based on normal controls were used to interpret the SNSB results. Scores ≥ 16th percentile, which were compared to–1 SD of the norm, were defined as normal. Severity of the cognitive complaints were assessed using a self-rated scale named cognitive failures questionnaire (total score 0–100, higher total score means more cognitive complaints).^{[8 (link)]} Using a self-report questionnaire, “informant also report a cognitive decline of the participant,” “subjective concern about the cognitive decline,” and “symptom’s onset after 65 years of age” were assessed at baseline and follow-up evaluations.