In a 300-mL two-necked round-bottomed flask
equipped with
a magnetic stirring bar, a rubber septum and an argon balloon, hexadecane-1,16-diol
(16.7 g, 64.8 mmol) in pyridine (130 mL), and TsCl (32.1 g, 168 mmol)
were added, respectively.16 (link) After stirring
for 12 h at 0 °C, ice water (100 mL) was added to quench the
reaction and filtered with the Büchner funnel washing with
ice water (50 mL) and cooled hexane (50 mL) to give a crude product,
which was recrystallized from toluene to give the titled compound2f (25.1 g, 68%).
equipped with
a magnetic stirring bar, a rubber septum and an argon balloon, hexadecane-1,16-diol
(16.7 g, 64.8 mmol) in pyridine (130 mL), and TsCl (32.1 g, 168 mmol)
were added, respectively.16 (link) After stirring
for 12 h at 0 °C, ice water (100 mL) was added to quench the
reaction and filtered with the Büchner funnel washing with
ice water (50 mL) and cooled hexane (50 mL) to give a crude product,
which was recrystallized from toluene to give the titled compound
