The intervention group received an oral supplement of 2000 mg nicotinamide orally 2-3 hours before chemotherapy. Additionally, they underwent carbogen gas inhalation (95% O2 and 5% CO2) starting 10 minutes before chemotherapy and continuing until the completion of the chemotherapy procedure. Inhalation was administered through a modified non-rebreathing mask at a flow rate of 10 liters/minute to minimize room air inhalation during carbogen administration. Conversely, the control group only underwent chemotherapy without any supplementary interventions.
Protocol detail
Nicotinamide and Carbogen for Chemo
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Corresponding Organization :
Other organizations : Dr. Kariadi Hospital, Diponegoro University, Mulawarman University, Lambung Mangkurat University
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Variable analysis
independent variables
- Oral supplement of 2000 mg nicotinamide
- Carbogen gas inhalation (95% O2 and 5% CO2)
- Outcome(s) measured from the chemotherapy procedure
- Chemotherapy procedure
- Negative control: The control group only underwent chemotherapy without any supplementary interventions.
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