The WB-MRI methodology used in this study has been previously described.[12 (link)] Briefly, using T1 and short-tau inversion recovery (STIR) technique on one of several 1.5T scanners (GE Healthcare, Milwaukee, Wisconsin), the entire body was imaged in the axial plane and then the spine and central base of the skull were imaged in the sagittal plane. Additionally, the axial diffusion-weighted imaging was performed in the axial plane (b-value 0 and 1,000 s/mm2). Overlapping acquisition field of views were confirmed to ensure complete anatomic coverage of the entire body, axial and appendicular skeleton, and adjacent soft tissues.Qualitative image evaluation was performed by a single dedicated onco-radiologist (EL) with approximately twenty years of experience reading WB-MRI. All reported reads are based on the clinical read at the time of imaging; the single false negative finding was re-read retrospectively.