Probiotics and Antibiotics in Piglet Growth

A total of 108 Duroc × Landrace × Yorkshire crossbred piglets (54 barrows and 54 gilts) were weaned at 21 ± 1 d of age (average initial BW 6.50 ± 0.21 kg), divided into 3 treatments (6 replicate pens/treatment, 6 piglets/pen according to BW and sex), and provided ad libitum access to feed and water. The 3 treatments included: a control group, an antibiotic group (a basal diet containing 40 g/t of virginiamycin and 500 g/t of chlortetracycline), and a probiotic group (basal diet + 1 × 10¹¹ CFU/kg BL−S6). Feed was given for 14 days. The test strain BL−S6 used in the present study was screened and preserved in the laboratory. The dry powder product of BL−S6 contained live bacteria at a concentration of 1 × 10¹¹ CFU/g. Diets for piglets were formulated based on the National Research Council (2012) and detailed in Supplementary Table S1.

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Sun W., Chen W., Meng K., Cai L., Li G., Li X, & Jiang X. (2023). Dietary Supplementation with Probiotic Bacillus licheniformis S6 Improves Intestinal Integrity via Modulating Intestinal Barrier Function and Microbial Diversity in Weaned Piglets. Biology, 12(2), 238.

Publication 2023

Antibiotic Bacteria Chlortetracycline Diets Powder Probiotic Replicate Strain Virginiamycin

Corresponding Organization : Ministry of Agriculture and Rural Affairs

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Variable analysis

independent variables

Diet type (control, antibiotic, probiotic)

dependent variables

Growth performance (not explicitly mentioned)

control variables

Age at weaning (21 ± 1 d)
Initial body weight (6.50 ± 0.21 kg)
Number of piglets per pen (6)
Ad libitum access to feed and water
Duration of feeding trial (14 days)

controls

Positive control: Antibiotic group (basal diet containing 40 g/t of virginiamycin and 500 g/t of chlortetracycline)
Negative control: Control group (basal diet without any additives)

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