Microglia depletion via pexidartinib
Corresponding Organization : Istituti di Ricovero e Cura a Carattere Scientifico
Other organizations : National Research Council, Istituto di Fisiologia Clinica, National Hospital for Neurology and Neurosurgery, University College London, Max Planck Institute of Experimental Medicine
Variable analysis
- Diet type: standard diet or PLX3397 (290 mg/kg) chow
- Microglia cell density in the CNS (reduced by more than 99%)
- Mouse genotype: WT and Cnp-Cre Jab1fl/fl
- Duration of diet: 21 days
- Positive control: Not specified
- Negative control: Standard diet group
Annotations
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