Measures of hDAT availability in the human brain had been collected using PET and [11C]cocaine, a radioligand to measure hDAT, and retrieved from the imaging dataset of the BNL Brain Imaging Center. All PET scans were performed on a Siemens, HR+ scanner in 3D mode via procedures as reported35 (link) along with the analytical approach to quantify the availability, which was estimated as Bmax/KD36 (link), 37 (link). For this study we only used data obtained in 62 healthy male controls (average age at 35.1 years with a standard deviation of 6.7; N=27 African Americans, 28 Caucasians, 3 Hispanics, and 4 multiracial).
Protocol detail
Quantifying Dopamine Transporter Availability
Partial Protocol Preview
This section provides a glimpse into the protocol.
The remaining content is hidden due to licensing restrictions, but the full text is available at the following link:
Access Free Full Text.
Corresponding Organization : Harvard University
Other organizations : New York University, Drexel University, National Institute on Alcohol Abuse and Alcoholism, Great Ormond Street Hospital, University College London, University of Alabama at Birmingham
Top 5 similar protocols
Variable analysis
independent variables
- None explicitly mentioned
- HDAT availability in the human brain, quantified as B_max/K_D
- Age (average 35.1 years with standard deviation of 6.7)
- Race (27 African Americans, 28 Caucasians, 3 Hispanics, and 4 multiracial)
- Positive control: None mentioned
- Negative control: None mentioned
Annotations
Based on most similar protocols
Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.
Sign up for free or login to display all annotations
As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!