Comprehensive Transcriptomic Analysis of CN-AML

All the microarray data used in our study were derived from the Gene Expression Omnibus (GEO) and were available for public downloading. Expression data for the 157 CN-AML patients in the primary cohort were detected using an Affymetrix HG-U133Plus 2.0 array [45 (link)], while the validating cohort of 162 CN-AML patients was evaluated using an Affymetrix HG-U133A array [49 (link)]. High-throughput sequencing data from The Cancer Genome Atlas (TCGA) were also used [50 (link)], including mRNA, microRNA and methylation data.

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Shi J.L., Fu L., Ang Q., Wang G.J., Zhu J, & Wang W.D. (2015). Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia. Oncotarget, 7(3), 2585-2595.

Publication 2015

HG-U133Plus 2.0 array HG-U133A array

Cancer Gene expression Genome Methylation Microarray Microrna Mrna Patients

Corresponding Organization :

Other organizations : Chinese PLA General Hospital, Peking University Third Hospital, Peking University

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Variable analysis

independent variables

Affymetrix HG-U133Plus 2.0 array
Affymetrix HG-U133A array
MRNA, microRNA and methylation data from The Cancer Genome Atlas (TCGA)

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

controls

No positive or negative controls specified

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