BioVU samples were genotyped using both the Affymetrix BioBank array and the Axiom World array 2 (Affymetrix Inc., Santa Clara, CA, USA) to attain better coverage for African-derived variants. BioME and the Mt. Sinai eMERGE site used the Illumina 1 M (Illumina Inc., San Diego, CA, USA) platform, with an exome chip backbone included for BioME samples. CARDIA-WS was genotyped on the Affymetrix 6.0 array (Affymetrix Inc., Santa Clara, CA, USA) as part of the Candidate-gene Association Resource which has been previously described in detail (Lettre et al. 2011 (link)).
The Stage 2 23andMe samples (1744 cases and 2906 controls) were genotyped on a custom GWAS panel across four versions. Stage 2 participants from BWHS (382 cases and 392 controls) were genotyped on the Illumina Infinium Expanded Multi-Ethnic Genotyping Array (MEGA; Illumina, Inc., San Diego, CA, USA) at Vanderbilt University VANTAGE Core Genotyping facility.