Downloading and Preprocessing GEO Dataset GSE2240

The Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm.nih.gov/geo, RRID:CVCL_VR24) is a public repository that provides access to high-throughput genomic datasets (Wang et al., 2019 (link)). We downloaded the GSE2240 datasets (Affymetrix GPL 96 platform. Affymetrix Human Genome U133A Array) from the GEO database to use in our analysis. Furthermore, the probes were converted into corresponding gene symbols based on the platform annotation information from the published data. The GSE2240 datasets contained 10 AF tissue samples and 20 SR tissue samples.

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Li Q., Lai Y., Gao X., Li X., Deng C.Y., Guo H., Zhao J., Yang H., Xu Y., Wu S., Xue Y, & Rao F. (2021). Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation. PeerJ, 9, e11488.

Publication 2021

GPL 96 platform Human Genome U133A Array

Gene Genomic Human genome Tissue

Corresponding Organization :

Other organizations : South China University of Technology, Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital

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Variable analysis

independent variables

Tissue type (AF vs. SR)

dependent variables

Gene expression levels

control variables

Affymetrix GPL 96 platform (Affymetrix Human Genome U133A Array)

controls

No positive or negative controls were explicitly mentioned.

Annotations

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