To a stirred solution of indoline-2-thione 1 (0.75 mmol,
1 equiv) and K2CO3 (104
mg, 0.75 mmol, 1 equiv) in CH3CN/H2O (97:3,
3 mL) at room temperature was added the RC adduct5 (0.75
mmol, 1 equiv). After the completion of the reaction (monitored by
TLC), the reaction mixture was concentrated in vacuo and the crude
residue was purified by silica gel column chromatography by gradient
elution with ethyl acetate/pet ether (10–25%).
1 equiv) and K2CO3 (104
mg, 0.75 mmol, 1 equiv) in CH3CN/H2O (97:3,
3 mL) at room temperature was added the RC adduct
mmol, 1 equiv). After the completion of the reaction (monitored by
TLC), the reaction mixture was concentrated in vacuo and the crude
residue was purified by silica gel column chromatography by gradient
elution with ethyl acetate/pet ether (10–25%).
