Mice in CFA+EA group received EA stimulation under anesthetization with 1% sevoflurane; Sham group and CFA group were similarly anesthetized at the same time. For the EA stimulation, 2 needles, 0.3 × 13 mm (Yunlong, China), were inserted at a depth of 1.5 mm in the right hind leg at acupoints corresponding to Zusanli (ST36) and Sanyinjiao (SP6), as described previously.22 (link) The needles were connected to HANS LH202H Han's acupoint nerve stimulator (Beijing Hua Wei Industrial Development Co, Beijing, China). Electroacupuncture stimulation (2-15 Hz alternating wave, 1.0 mA) was initiated after CFA injection and lasted for 30 minutes. This process was repeated every 2 days (Fig.
Electroacupuncture Alleviates Inflammatory Pain
Mice in CFA+EA group received EA stimulation under anesthetization with 1% sevoflurane; Sham group and CFA group were similarly anesthetized at the same time. For the EA stimulation, 2 needles, 0.3 × 13 mm (Yunlong, China), were inserted at a depth of 1.5 mm in the right hind leg at acupoints corresponding to Zusanli (ST36) and Sanyinjiao (SP6), as described previously.22 (link) The needles were connected to HANS LH202H Han's acupoint nerve stimulator (Beijing Hua Wei Industrial Development Co, Beijing, China). Electroacupuncture stimulation (2-15 Hz alternating wave, 1.0 mA) was initiated after CFA injection and lasted for 30 minutes. This process was repeated every 2 days (Fig.
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Corresponding Organization :
Other organizations : Wenzhou Medical University, First Affiliated Hospital of Wenzhou Medical University, Wenzhou Central Hospital, Hangzhou Medical College, Zhejiang Provincial People's Hospital, Wenzhou City People's Hospital
Protocol cited in 4 other protocols
Variable analysis
- CFA injection
- Electroacupuncture (EA) stimulation
- Inflammatory pain response
- Injection of phosphate-buffered saline (Sham group)
- Sham electroacupuncture (SEA) without electrical stimulation or manual needle manipulation
- Positive control: CFA group
- Negative control: Sham group
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