EORTC QLQ-C30 for Assessing QoL in Allo-HSCT

The European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (QLQ-C30) was used to assess QoL at baseline (i.e., on day 8 or 7 before allo-HSCT) [19 (link)]. The QLQ-C30 includes five functional scales (role, physical, cognitive, emotional and social), three symptom scales (nausea/vomiting, fatigue, and pain), and six single items (insomnia, dyspnea, appetite loss, constipation, diarrhea, and financial problems). This questionnaire also includes a global health status/quality of life (QoL) scale. All scales and single items are transformed into standardized scores ranging from 0 to 100, with higher scores for the functioning scales and global health status/QoL scale indicating better outcomes, while higher scores on the symptom scales and single items indicate greater symptom severity [19 (link)].

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Gudmundstuen A.M., Efficace F., Tjønnfjord G.E., Skaarud K.J., Cottone F., Hjermstad M.J, & Iversen P.O. (2023). The prognostic value of patient-reported outcomes in allogeneic hematopoietic stem cell transplantation: exploratory analysis of a randomized nutrition intervention trial. Annals of Hematology, 102(4), 927-935.

Publication 2023

Allo 7 Appetite loss Cancer Cognitive Constipation Diarrhea Dyspnea Emotional European Fatigue Insomnia Nausea Pain Physical

Corresponding Organization : University of Oslo

Other organizations : Fondazione Gimema Onlus, Lovisenberg Diakonale Høgskole

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Variable analysis

independent variables

No independent variables explicitly mentioned.

dependent variables

Quality of Life (QoL) measured using the QLQ-C30 questionnaire, including:
- Five functional scales (role, physical, cognitive, emotional, and social)
- Three symptom scales (nausea/vomiting, fatigue, and pain)
- Six single items (insomnia, dyspnea, appetite loss, constipation, diarrhea, and financial problems)
- Global health status/quality of life (QoL) scale

control variables

No control variables explicitly mentioned.

positive controls

None specified.

negative controls

None specified.

Annotations

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